Joe Rogan Experience #1349 – David Sinclair

David Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. His new book “Lifespan: Why We Age And Why We Don’t Have To” is now available.

48 thoughts on “Joe Rogan Experience #1349 – David Sinclair

  1. Sinclair is involved either as a founder, an investor, an equity holder, a consultant or a board member with 28 companies, according to a list of his financial interests. At least 18 are involved in anti-aging in some way, including studying or commercializing NAD boosters. The interests range from longevity research startups aimed at humans and even pets to developing a product for a French skin care company to advising a longevity investment fund. He’s also an inventor named in the patent licensed by Harvard and the Mayo Clinic to Elysium, and one of his companies, MetroBiotech, has filed a patent related to nicotinamide mononucleotide.

    In 2004, Sinclair co-founded a company, Sirtris, to test resveratrol’s potential benefits and declared in an interview with the journal Science it was “as close to a miraculous molecule as you can find.” GlaxoSmithKline bought the company in 2008 for $720 million. By the time Glaxo halted the research in 2010 because of underwhelming results with possible side effects, Sinclair had already received $8 million from the sale, according to Securities and Exchange Commission documents. He also had earned $297,000 a year in consulting fees from the company, according to The Wall Street Journal.

    Liberty Biosecurity, a company he co-founded, estimated in Sinclair’s online bio that he has been involved in ventures that “have attracted more than a billion dollars in investment.” When KHN asked him to detail the characterization, he said it was inaccurate, without elaborating, and the comments later disappeared from the website.

    Harvard declined to release Sinclair’s conflict-of-interest statements, which university policy requires faculty at the medical school to file in order to “protect against any faculty bias that could heighten the risk of harm to human research participants or recipients of products resulting from such research.”

  2. This Sinclair guy is a moran when I listen to guys like that I no wonder why our medical world sucks
    Just go to Europe and ask every farmer about meat milk etc they know this stuff for generations. Moran !!!!!!!!

  3. In reference to the eating human meat there was a crazy chick at a meeting in the last two months run by Ocasio-Cortez talking about how we need to eat the babies to stop the greenhouse effect AND Cortez didn’t say anything to shut this bitch down. So ya people are talking about it and it’s pretty fucking mental as far as I’m concerned.

    I lived on a dairy farm in Utah for a couple of years and fresh ice cold milk taken from the milk tank is and was the best milk I ever had.

  4. My biggest question is if resveratrol will work better at lower doses in people who workout a lot since a little bit of the stress in the body could be beneficial would that amount of resveratrol plus fasting and intense workout could that be to much stress?

  5. I'll love to participate in the study for a $1 I'll do it for free also but i understand the ethics of it ( I'll love to participate voluntarily)!!

  6. Hey, just sayin'… This is the way we, in Bulgaria have been making yoghurt for centuries. The "packages" you put in is actually a bacteria called "bacilicus bulgaricus" and it originates from here( where the name comes from) .
    The thing is once you make it, you can use the newly formed yoghurt to put in new fresh milk, instead of buying new packages. It's the same process.

  7. One problem with taking resveratrol is that while it is well absorbed in humans, it is rapidly metabolized so that only 1% bioavailability is achieved. So if you take 1 g only 10mg is available to provide any benefit.

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